中文摘要：

理想的肿瘤治疗制剂能特异性地靶向于肿瘤细胞，起到安全有效的药物传递作用。核酸适配体非同寻常的分子识别能力使得其成为最具前景的生物靶向分子。笔者从结合方式、载体种类等方面，以有代表性的核酸适配体与靶向制剂结合文献资料为依据，进行归纳、总结，综述了近5年来核酸适配体用于靶向肿瘤制剂构建的最新研究进展，并对存在的问题进行了分析与展望。

英文摘要：

Ideal preparation of cancer therapy could specifically target to tumor cells, serving as safe and effective drug delivery system. With peculiar molecular recognition ability, aptamers become the most promising biological target molecules. This review was based on representative literatures, and the data was summarized and analyzed. It summarizes the latest research progress of aptamers modified targeted tumor preparation in the past five years from tethered way and carriers type, and the existing problems are analyzed and prospected.