下一代的定序(NGS ) 与它的高产量的能力和低费用,技术在最近的年里很快发展了并且为许多 genomics 研究人员成为一个重要分析工具。在法庭的研究的研究领域的新机会由利用 NGS 技术的力量出现,它能被用于同时分析对不同基因上下文的法庭的兴趣的多重 loci,例如正染色体, mitochondrial 和性染色体。而且, NGS 技术能也在研究的许多另外的方面有潜在的应用程序。这些包括推理, monozygotic 双胞胎研究,身体液体和种类鉴定,和法庭的动物,植物和 microbiological 分析的 DNA 数据库建设,祖先和 phenotypic。这里,我们与为未来辩论术研究和惯例提供引用的目的在法庭的科学的领域里考察 NGS 技术的应用程序。
Next-generation sequencing (NGS) technology, with its high-throughput capacity and low cost, has developed rapidly in recent years and become an important analytical tool for many genomics researchers. New opportunities in the research domain of the forensic studies emerge by harnessing the power of NGS technology, which can be applied to simultaneously analyzing multi- ple loci of forensic interest in different genetic contexts, such as autosomes, mitochondrial and sex chromosomes. Furthermore, NGS technology can also have potential applications in many other aspects of research. These include DNA database construction, ancestry and phenotypic inference, monozygotic twin studies, body fluid and species identification, and forensic animal, plant and microbiological analyses. Here we review the application of NGS technology in the field of forensic science with the aim of providing a reference for future forensics studies and practice.