中文摘要：

一个简单、有效的一个壶过程为 pyrrolo 的构造被开发了[1,2-a ] 经由 5-aminopyrazoles， acetylenedicarboxylates 和 malononitrile 在下面的三部件的牙齿反应的嘧啶没有催化剂，微波照耀条件。在这转变的关键步骤是 5-aminopyrazole 底层的 NN 契约劈开反应，它在这研究第一次在这上下文被报导了。这个协议的优点包括容易地可得到的开始的材料，短反应时间和好 regioselectivity。

英文摘要：

A simple and efficient one-pot procedure has been developed for the construction of pyrrolo[ 1,2-a]pyrimidines via the three-component domino reaction of 5-aminopyrazoles, acetylenedicarboxylates and malononitrile under catalyst-free, microwave irradiation conditions. The key step in this transformation is the N--N bond cleavage reac- tion of the 5-aminopyrazole substrate, which has been reported in this context for the first time in this study. The advantages of this protocol include readily available starting materials, short reaction times and good regioselectivity.