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Evaluating effects of gypenosides and soyasaponins on differentiation of neural stem cells as an in vitro model
  • 分类:Q2[生物学—细胞生物学]
  • 作者机构:[1]Laboratory of Neural Molecular Biology, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China
  • 相关基金:Project supported by the National Basic Research Program of China (Grant No.2006CB500702), the National Natural Science Foundation of China (Grant No.30570590), and the Science Foundation of Shanghai Municipal Commission of Science and Technology (Grant No.03JC14030)
中文摘要:

神经干细胞有一个潜力区分进神经原,星形细胞和 oligodendrocytes。它提供一在里面在细胞的区别和发展水平上屏蔽草药的药的 vitro 模型。在这个工作,从 gypenosides 和 soyasaponins 的活性组份被准备在神经干细胞的区别上调查他们的效果。gypenosides 和 soyasaponins 支持神经干细胞的区别。这个方法为屏蔽有效的草药的药提供速度和实物。它很好适合学习房间区别和开发的机制。

英文摘要:

Neural stem cell has a potential to differentiate into neurons, astrocytes and oligodendrocytes. It provides an in vitro model to screen herbal medicines on the cellular differentiation and development level. In this work, active component from gypenosides and soyasaponins was prepared to investigate their effects on the differentiation of neural stem cells.. Both gypenosides and soyasaponins promote the differentiation of neural stem cells. This method provides speed and practicality for screening effective herbal medicine. It is well suited for studying the mechanism of cell differentiation and development.

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