目的 研究毛萼紫薇(Lagerstroemia balansae Koehne)的化学成分。方法采用各种色谱技术分离纯化化合物,并通过理化性质和波谱学方法鉴定化合物的结构。结果从毛萼紫薇茎的95%乙醇提取物中分离得到7个化合物,分别鉴定为ficuscarpanoside A(Ⅰ)、反式-阿魏酸二十八烷酯(trans—femlicacidoctacosyl ester,11)、lyoniside(Ⅲ)、gomisin N(Ⅳ)、正一三十烷醇(n—tfiacontanol,Ⅴ)、β-谷甾醇(β-sitosterol,Ⅵ)和胡萝卜苷(daucosterol,Ⅶ)。结论以上化合物均为首次从该植物中获得,其中化合物Ⅰ~Ⅴ为首次从紫薇属植物中分离得到。同时本实验还在2D—NMR的基础上对化合物Ⅰ在DMSO-d6中的1H—NMR和13C—NMR数据以及化合物Ⅰ在DMSO—d6中的1H—NMR数据进行了全归属,并纠正了文献中化合物Ⅲ13C—NMR数据的错误归属。
OBJECTIVE To study the chemical constituents of Lagerstroemia balansae Koehne. METHODS The crude herb of the stems of L. balansae was extracted with 95% EtOH and isolated by repeated chromatographic methods. The structures of the isolated compounds were elucidated by physicochemical and spectral analysis. RESULTS Seven compounds were yielded and identified as: ficuscarpanoside A ( Ⅰ), trans-ferulic acid octacosyl ester ( Ⅱ ) , lyoniside ( Ⅲ), gomisin N ( Ⅳ), n-triacontanol ( Ⅴ), β-sitosterol (Ⅵ) and daucosterol ( Ⅶ ). CONCLUSION All compounds were isolated from this plant for the first time, and compound ( Ⅰ - Ⅴ) were obtained from the genus Lagerstroemia for the first time. On the basis of 2D-NMR spectra the 1 H and 13 C-NMR signals of Ⅰ , the 1H-NMR signals of m in DMSO-d6 were assigned totally and the uncorrected assignment of 13C-NMR signals of Ⅲ in the literature were revised.