中文摘要：

以苯乙酮与间苯二甲酸甲酯为原料经由Claisen缩合制备了1,3-二（3-苯基-3-氧代丙烯醇）苯（BPOB）.用元素分析、MS、1H NMR、UV吸收光谱、X射线单晶衍射和固体CD光谱等对其进行了表征.晶体结构数据显示,BPOB属于Sohncke空间群P212121,UV和1H NMR谱表明,BPOB在溶液中主要以烯醇式存在,固体CD光谱和重结晶实验证明,BPOB手性晶体的形成是结晶诱导的绝对不对称合成.

英文摘要：

1,3-bis （3-phenyl-3-oxopropanoyl）benzene （BPOB） was prepared by Claisen condensation of acetophenone and dimethyl isophthalate and characterized by elemental analysis, MS, 1H NMR, UV absorption spectrum, solid-state circular dichroism （CD） spectra, and X-ray single-crystal diffraction. The X-ray crystallographic data indicated that BPOB crystallized in a Sohncke group P212121, UV and 1H NMR showed that the enol tautomer was the most dominant form in solution, and the solid-state CD spectra and repeated recrytallization revealed that the formation of chiral BPOB crystals could be regarded as crystallization-induced asymmetric synthesis.