目的探讨共享伽玛脆弱模型在癫痫复发事件数据的应用及R软件实现。方法收集癫痫复发数据,构建共享脆弱模型,利用伽玛脆弱来解释事件间的相关性。结果共享脆弱模型可以用来评价癫痫复发临床疗效,结果解释合理,R软件容易实现。结论共享脆弱模型可以很好地处理复发事件数据间的相关性。
ObjectiveTo explore the applications of shared gamma frailty models in recurrent event data about epileptic seizures,and implement of R software. MethodsCollecting the epileptic seizures data,establishing the shared frailty models,explaining the correlation between event times using gamma frailty. Results We can evaluate the clinical effect of epileptic seizures data using shared gamma frailty models,the explain is reasonable,the implement of R software is easy. ConclusionShared frailty models are useful for handling dependence in recurrent events data.