中文摘要：

目的探讨儿童烟雾病患者头痛的临床特征、脑硬膜-动脉血管融通术（EDAS）疗效及影响治疗效果的因素。方法回顾性分析2004年1月至2013年12月,解放军第三○七医院神经外科收治的513例儿童烟雾病患者的临床资料,筛选出有头痛症状并经EDAS治疗的患者103例,对所有患者通过电话及住院随访6~144个月。分析103例患者头痛的临床特征和EDAS疗效,根据患者术后头痛的缓解情况,分为头痛消失组86例和头痛缓解组17例。另将103例中,71例首发症状为头痛的患者分为单纯头痛者16例和头痛后出现其他症状者55例,比较影响头痛治疗效果的相关因素。结果 （1）EDAS后头痛消失组与头痛缓解组之间的性别、年龄、受累血管支数、铃木分期、头痛严重程度差异无统计学意义（P〉0.05）。103例中,87例患者就诊时有短暂性脑缺血发作症状,头痛主要位于额、颞部,性质多为胀痛;86例患者EDAS后头痛消失,17例患者术后头痛改善。（2）单纯性头痛患者的铃木分期与头痛后出现其他症状患者的铃木分期比较,差异有统计学意义（Z=4.422,P〈0.01）。结论头痛可能是儿童烟雾病患者的早期症状及后续出现其他症状的预警信号,单纯性头痛患者的铃木分期较头痛后出现其他症状患者的铃木分期低,EDAS能够改善儿童烟雾病患者的头痛症状。

英文摘要：

Objective To investigate the clinical features of headache, the efficacy of encephalo- duro-arterio-synangiosis （EDAS）,and the factors affecting the treatment effect in children with moyamoya disease. Methods The clinical data of 513 children with moyamoya disease admitted to the Department of Neurosurgery, the 307 th Hospital of People＇s Liberation Army from January 2004 to December 2013 were analyzed retrospectively. A total 103 children had headache symptoms and were treated with EDAS. All the children were followed up through telephone or hospitalization for 6 - 144 months. The clinical features and efficacy of EDAS of 103 children were analyzed. They were divided into a headache complete remission group （ n = 86） and a non-complete remission group （ n = 17） according to remission condition of headache after procedure. Seventy-one of 103 children with the first headache symptom were divided into a simple headache group （n = 16） and a group of having other symptoms after headache （ n = 55 ）. The related factors influencing the therapeutic effect of headache were compared. Results （ 1 ） There were no significant differences in age, gender, number of suffered vessels, Suzuki stage, and severity of headache after EDAS between the complete remission group and the non-complete remission group （P 〉 0.05）. In 103 children, 87 had the symptoms of transient ischemic attack at the time of presentation. Headache mainly located in the frontal and temporal lobes, and its nature was distending pain. The headache disappeared in 86 children after EDAS. The headache of 17 children was improved after procedure. （2） There was significant difference in Suzuki stage in children with simple headache and those having other symptoms after headache between the 2 groups （Z = 4.422 ,P 〈 0.01 ）. Conclusions Headache may be an early warning signal for the early symptoms in children with moyamoya disease and other subsequent symptoms. The Suzuki stage in patients with simple headache is lower than