中文摘要：

肿瘤的生长、转移有其途径,为探讨血管生成因子与胃癌的生长、转移之间的相关性,运用文献研究的方法,查阅近年来相关文献,总结了其密切关系：VEGF、bFGF对胃癌的生长起重要的促进作用;VEGF、VEGF-C的表达和MVD值与胃癌淋巴结转移、Borrmann分型、肿瘤分化程度和生长方式相关,而且肿瘤细胞和肿瘤血管中的VEGF、bFGF作为能被检测的成分,在肿瘤的诊断、靶向治疗定位和预后判断中起重要作用。因此,抑制VEGF、bFGF、VEGF-C的表达,降低MVD值可作为治疗胃癌的有效作用靶点,为胃癌的疗效评价提供了客观指标。

英文摘要：

Different cancer has its own ways of growth and metastasis.To study the relativity between angiogenesis factors and gastric cancer,we applied literature method to consult a number of books about the subject,and sum up as follows：VEGF and bFGF are stimulative to the growth of Gastric Cancer;expression of VEGF、VEGF-C and the value of MVD are relative to the lymph node metastasis、Borrmann typing、carcinoma differentiation degree and growth pattern in gastric carcinoma.And VEGF、bFGF which can be detected in carcinoma cells and vessels play an important role in the diagnosis,targeted treatment and prognosis of cancer.So restraining the expression of VEGF、bFGF、VEGF-C and reducing the MVD value will be the effective treated target.It can provide objective indexes to the evaluation of treatment.