中文摘要：

目的比较更年安神方加阿普唑仑组和阿普唑仑组治疗阴虚火旺证失眠患者,在治疗前后主观症状、失眠测评量表积分方面的变化,探讨更年安神方的临床意义。方法选取72例符合纳入标准的单纯性失眠患者,分组纳入治疗组和对照组各36例,连续治疗4周。结果治疗组有效率88.89%;对照组有效率77.78%;2组均可改善睡眠,降低患者的匹兹堡睡眠品质量表（PSQI）积分;2组均能使血中5-羟色胺（5-HT）水平上升、去甲肾上腺素（NE）水平下降。结论更年安神方治疗阴虚火旺证失眠患者临床疗效确切。

英文摘要：

Objective Compare GengNianAnShen Decoction Combined with alprazolam group with alprazolam group to treat patients with hyperactivity of fire and yin deficiency type insomnia,in the change of before and after subjective symptoms and insomnia assessment scale scores, effection on serum 5-Hydroxy tryptamine （5-HT）, norepinephrine （NE）, to investigate the clinical significance of GengNianAnShen Decoction. Methods Select 72 cases of simple insomnia patients met the inclusion cri- teria,divided into treatment group and control group, each include 36 cases, continuous treatment for 4 weeks. Results The ef- fective rate of the treatment group was 88.89% ,77.78 % of the control group;Both groups could improve sleep, reduce PSQI integral of the patients; Both groups could rise serotonin and reduce norepinephrine in the serum level. Conclusion GengNianAnShen Decoction had clinical efficacy in treating patients with hyperactivity of fire and yin deficiency type insomnia, could ameliorate the level of serotonin and norepinephrine in the serum level.