Sulfated tyrosines 27 and 29 in the N-terminus of human CXCR3 participate in binding native IP-10
ISSN号:1671-4083
期刊名称:《中国药理学报:英文版》
时间:0
分类:R33[医药卫生—人体生理学;医药卫生—基础医学]
作者机构:[1]Department of Respiratory Disease,Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China, [2]Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100088, China, [3]Department of Microbiology and Molecular Genetics, Division of AIDS, Harvard Medical School, Boston, Massachusetts 02115, USA, [4]Department of Biochemistry and National Laboratory of Medical Molecular Biology Basic Institute of Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100005, China
相关基金:Acknowledgements This work was supported in part by grants from the National Natural Science Foundation of China (No 30470767), the Beijing Natural Science Foundation (No 7072063), and the Ministry of Education of China (No NCET 06-0156). We are grateful to Dr Hyeryun CHOE for helpful encouragement and plasmids, Dr Paulette L WRIGHT for critical reading and editing of this manuscript, Drs Wei CUI and Ding-hua LIU for assistance with FACS analysis and Dr Zhi-ying ZHAO for help in performing binding experiments.