中文摘要：

泛素蛋白酶体碳末端水解酶L3（Ubiquitin C-terminal hydrolases L3，UCH-L3）是泛素蛋白酶体中碳末端水解酶的一种，可以将泛素分子从底物上水解下来，使得泛素蛋白酶体在细胞内再循环利用。目前对UCH-L3的研究还不充分，近年来发现它在多种疾病中都呈现高表达，可能与多种疾病的发生和发展有一定的联系。

英文摘要：

Ubiquitin C-terminal hydrolases L3 （UCH-L3） is a C-terminal hydrolase in ubiquitin-proteasome. Ubiquitin can be hydrolyzed from the substrate, so that the ubiquitin-proteasome can be recycled in the cells. In recent years, scientists have found that UCH-L3 highly expressed in several diseases such as neoplasms, obesity, etc., which may be related to the occurrence and development of these diseases.