中文摘要：

目的 揭示我国汉族人群FcαR1基因多态性的分布规律。方法 提取100例正常广东汉族人基因组，分段扩增FcαR1基因并直接测序鉴定基因型。结果 ①共发现我国汉族人群FcαR1基因内各类多态位点34个，以SNPs最常见（88．24％），其中新发现多态位点（最新数据库资料未报道）21个；②多态性位点在FcαR1基因内的具体分布状况如下：调控区有10个（29．4％），外显子区共9个（26．5％），内舍子区15个（44．1％，其中交界区8个，23．5％）。结论 我国汉族人群FcαR1基因多态性分布特征不同于数据库资料，提示我国汉族人群基因结构与高加索人群有显著性差异。

英文摘要：

Objectivec To investigate the distribution of Chinese population. Methods Genomic DNA was extracted the polymorphisms in Fc a RI gene in the form 100 healthy Chinese Han subjects. Genotype of the polymorphisms in Fc α RI gene were determined by polymerase chain reaction （PCR） and sequencing. Results 1, There are 34 polymorphisms loci in Fc α R1 gene, SNPs occupied most loci （88. 24%）, 21 variance were first found among the total 34 loci . 2. the distribution of the polymorphisms were as follows： 10 in regulator region （29.4%）;9 in exon （26.5%） and 15 in intron （44. 1%, 8 in junctional zone, 23.5%） Conclusion The polymorphisms of Fc α R1 gene in the Chinese Han population were Significantly different from the data base documente. The results may implicated different gene construction in the Chinese and other populations,