中文摘要：

[目的]探讨新生儿经大隐静脉置入中心静脉导管的安全性及有效性。[方法]对52例新生儿（观察组）经大隐静脉置入中心静脉导管，75例（对照组）经肘部静脉置入中心静脉导管。比较两组患儿一次穿刺成功及上（下）腔静脉一次到位情况、并发症发生情况、非计划性拔管情况。[结果]观察组一次到位率高于对照组（P〈0．05）；观察组液体外渗发生率、非计划性拔管率低于对照组（P〈0．05）。[结论]经大隐静脉置入中心静脉导管安全有效，可作为新生儿经外周静脉置入中心静脉导管的备选途径。

英文摘要：

Objective. To probe into the safety and efficacy of central venous catheter inserted via great saphenous vein （GSV） in neonates. Methods. 52 cases of newborns （study group） accepting central venous catheter inserted via great saphenous vein and 75 newborns （control group） accepting central venous catheter inserted via elbow vein were selected for a ret- rospective study,the to compare the success rate,the rate of nonplan extubation and occurrence of complications. Results. The rate of one place in observation group was higher than that of control group（P〈0.05）;the incidence of infiltration and rate of non-plan extubation in observation group were lower than that in control group（P〈0.05）. Conclusion. Inserting central catheter via the great saphenous vein is safe and effective which can be selected method for peripherally inserted central catheter in neonates