中文摘要：

目的：通过对经新生儿大隐静脉置入中心静脉导管手段的观察，分析临床采用该法的安全性及可实施性。方法：采用回顾性分析法，对同期152例经大隐静脉和82例经肘部静脉置人中心静脉导管患儿的一次穿刺成功率、上（下）腔静脉一次到位率、机械性静脉炎、导管相关血流感染、导管堵塞、液体外渗情况进行比较分析。结果：两组一次穿刺成功率比较差异有统计学意义（P〈0．05）；大隐静脉组下腔静脉一次到位率、肘部静脉组上腔静脉一次到位率比较差异有统计学意义（P〈0．05）；两组在静脉炎、液体外渗、导管相关性血流感染、导管堵塞发生率方面比较，差异无统计学意义（P〉0．05）。结论：对于危重新生儿，采用经大隐静脉置人中心静脉导管的安全性和有效性明显高于肘部静脉置人中心静脉导管方式。

英文摘要：

Objective：To explore the effect of inserting central catheter via the great saphenous vein （GSV） in neonates. Methods：A retrospective study was conducted, the success rate, the rate of non - plan extubation and complications of 152 cases of inserting central catheter via great saphenous were compared with 82 cases which were inserted central catheter via elbow vein. Results：The two groups of one - time successful puncture rate compared was statistically significant （ P 〈 0.05） ;great saphenous vein group of inferior vena cava once in place rate, elbow vein group superior vena cava once in place rate difference was statistically significant （P 〈 0.05 ） ;the two groups in the phlebitis, liquid leakage, catheter related bloodstream infection, catheter blockage rate compared no significant difference （P 〉0.05）. Conclusion：Inserting central catheter via the great saphenous vein is safe and effective in neonates,the great saphenous vein can be a choice for PICC.