中文摘要：

目的调查云南省昭通市氟中毒病区居民发氟、砷、硒水平，为氟中毒病区居民健康状况的评价及氟中毒防治提供参考依据。方法在昭通市氟中毒病区县（镇雄、威信县）采集居民发样65份，其中41份发样采自6个病区乡镇的中、重度氟斑牙患者，24份发样采自作为对照的1个非病区乡，发样含氟量用高温燃烧水解-氟离子选择电极法测定，含砷、硒量用原子荧光法测定。结果氟中毒患者的41份发样中，氟、砷、硒的平均水平分别为（19．09±18．36）、（1．50±1．04）、（2．87±3．12）mg／kg；对照居民的24份发样中，氟、砷、硒平均水平分别为（17．02±16．63）、（0．29±0．22）、（1．28±0．73）mg／kg。氟中毒患者与对照居民发氟水平比较，差异无统计学意义（P〉0．05），而发砷、硒水平差异有统计学意义（P〈0．05）。结论昭通市氟中毒病区存在轻度砷污染．可能会加重病区氟中毒的发生与流行。高氟混煤烘烤后的粮食在给居民造成氟中毒的同时，可能也带来了硒元素的补充。

英文摘要：

Objective To assess the fluorine （F）, arsenic （As） and selenium （Se） levels in hair of residents from the fluorosis area of Zhaotong and provide reference basis for the evaluation of the health status of populations in fluorosis areas as well as the prevention and control of fluorosis in Zhaotong. Methods Sixty-five hair samples were collected in fluorosis areas（Zhenxiong, Weixin County）, including. 41 samples from 6 endemic townships and 24 samples from a non-endemic township. Fluorine content in hair was determined by combustionhydrolysis-ion selective electrode method. Arsenic and selenium contents in hair were determined by atomfluorescence method. Results The average contents of hair fluorine, arsenic and selenium contents were （15.1807 ± 15.2397）, （2.1806± 1.9601）, （2.3162 ± 2.4535）mg/kg in the 41 patients with fluorosis and were （18.7703 ± 17.1067 ）, 0.3283 ± 0.2466 ）, （1.2805 ± 0.6970）mg/kg in the 24 inhabitants （control）. The difference of fluorine content in hair between patients in fluorosis and control inhabitants was not statistically significant （P 〉 0.05 ）, but the difference in arsenic and selenium content was statistically significant （P 〈 0.05 ）. Conclusions Mild arsenic pollution exists in Zhaotong fluorosis areas, which aggravates the prevalence of fluorosis. Food roasted with blended coal contains high fluorine. Meanwhile it may bring in the supplement of selenium for the inhabitants in Zhaotong fluorosis areas.