大量研究表明肿瘤细胞可表达β受体,而一些神经递质、药物和社会心理因素可能通过β受体影响肿瘤的生长和转移,β受体激动剂、β受体阻滞剂以及抑郁等社会心理因素可加强或削弱这种作用。这为表达β受体肿瘤的治疗开辟了新的道路,提供了新的治疗靶点。
A lot of researches have demonstrated that tumor cells can express beta-adrenoceptors through which some neurotransmitters, drugs and psychosoeial factors may affect the development and metastasis of tumors. And this effect can be enhanced or attenuated by agonists or antagonists of beta-adrenoceptors and depression. This opens up new avenues and offers promising therapeutic targets for tumors expressing beta-adrenoceptors.