吡唑类化合物是一类重要的药物合成中间体,在抗肿瘤、抗病毒、抗抑郁等领域发挥着重要作用。本文综述了吡唑类衍生物的合成方法,包括1,3-亲电化合物与肼类的环化、1,3-偶极体系的环加成等。
Pyrazole derivatives are important intermediates in pharmaceutical synthesis and play significant roles in antieancer, antiviral, and antidepression. Progress in syntheses of pyrazole derivatives, including cyelocondensation of 1, 3-dielectrophilic compounds with hydrazines and 1,3-dipolar cyeloadditions methods are summarized.