Tyrosinase 在有机体普遍存在并且是一个典型的酶 ofmelanocytes.Tyrosinase 家庭在脊椎动物的基因由 3 个相关成员组成; tyrosinase (TYR, Tyr ) , tyrosinase 相关的 protein-1 (TRP-1, Tyrpl ) ,并且 tyrosinase 相关的 protein-2 (TRP-2, Tyrp2, Dct ) 。这些蛋白质在颜料房间催化黑素生合成并且在决定脊椎动物着色法起重要作用。TYR 和 TRP 基因的抄写为在胚胎开始期间学习神经的冠和眼的泡房间移植和区别是有用的并且在在鱼的颜料营救重要。在这篇论文,在鱼的 TYR 家庭的基因和蛋白质分子进化,功能和角色的结构被考察。
Tyrosinase exists universally in organisms and is a characteristic enzyme of melanocytes. Tyrosinase family genes in vertebrates consist of 3 related members; tyrosinase (TYR, Tyr), tyro sinase-related protein-1 (TRP-1, Tyrp 1), and tyro sinase-related protein-2 (TRP-2, Tyrp2, Dct). These proteins catalyze melanin biosynthesis in pigment cells and play important roles in determining vertebrate coloration. Transcription of the TYR and TRP genes is useful for studying neural crest and optic vesicle cell migration and differentiation during emblyogenesis and important in pigment rescue in fish. In this paper, the structure of gene and protein molecular evolution, function and roles of the TYR family in fish were reviewed.