中文摘要：

脂质体具有类似生物膜的双分子层结构,利用电形成法制备的脂质体多为10—100μm的巨型单层囊泡,在光学显微镜下容易观察,因此利用电形成法制备的脂质体在模拟和替代细胞等方面的研究和应用具有较大潜力。本文对电形成法制备脂质体的研究进行了综述。文中介绍了传统的及改进后的电形成装置,对双分子层厚度、渗透压、电解质、固体表面、电压、频率、温度、pH值等过程参数对脂质体形成的影响作了详细阐述。

英文摘要：

Liposomes have bilayer structure,which is similar to that of bio-membrane.Most liposomes obtained by the electroformation method are giant unilamellar vesicles（diameter 10—100 μm）,which can be observed under optical microscope easily.So they have great potential in simulation,replacement cells and other aspects.This paper reviews the influence of electric field on liposome formation and introduces the traditional and modified electroformation setup.We also elaborate the influence of process parameters on liposome formation,such as bilayer thickness,osmotic pressure,electrolyte,solid surface,voltage,frequency,temperature,pH value,etc.