中文摘要：

神经系统的最显著的特征是大脑的发展和功能被出生后的经验大部分重塑，在有基因风景的关节。性质对养育参数提醒我们基因并且 epigenetic 信息为大脑的正常函数是不可缺少的。epigenetic 在中央神经系统的规章的机制被揭示了在上一十年持续。而且， epigenetic 调节的人基因的变化被显示了在 neuropsychiatric 混乱被含有，例如孤独性光谱混乱。epigenetic 学习为时间的一个相对短时期在神经科学领域里开始了。在这评论，我们将在神经开发关于 epigenetic 规定总结最近的发现， synaptic 粘性，学习并且存储器，以及 neuropsychiatric 混乱。尽管 epigenetic 规定怎么贡献大脑的功能的全面看法没被完成，观点那个大脑，有机体的最复杂的机关，被 epigenetic 开关深刻地塑造广泛地被接受。

英文摘要：

The most remarkable feature of the nervous system is that the development and functions of the brain are largely reshaped by postnatal experiences, in joint with genetic landscapes. The nature vs. nurture argument reminds us that both genetic and epigenetic information is indispensable for the normal function of the brain. The epigenetic regulatory mechanisms in the central nervous system have been revealed over last a decade. Moreover, the mutations of epigenetic modulator genes have been shown to be implicated in neuropsychiatric disorders, such as autism spectrum disorders. The epigenetic study has initiated in the neuroscience field for a relative short period of time. In this review, we will summarize recent discoveries about epigenetic regulation on neural development, synaptic plasticity, learning and memory, as well as neuropsychiatric disorders. Although the comprehensive view of how epigenetic regulation contributes to the function of the brain is still not completed, the notion that brain, the most complicated organ of organisms, is profoundly shaped by epigenetic switches is widely accepted.