中文摘要：

对海南粗榧（Cephalotaxus hainanensis Li）内生真菌S15次生代谢产物进行了研究。用多种柱色谱技术从S15的发酵液中分离得到2个化合物,根据波谱数据和理化性质将其鉴定为乙酰基细胞松弛素D（1）和细胞松弛素D（2）,对其进行生物活性测试,发现2种细胞松弛素对肿瘤细胞SGC-7901有强细胞毒活性。

英文摘要：

Secondary metabolites from the endophytic fungus S15 from Hainan plum-yew （Cephalotaxus hainanensis Li） were studied. Two constituents were isolated and purified by multiple column chromatography, and their structures were identified as acetyl cytochalasin D （1） and cytochalasin D （2） by physicochemical and spectroscopic data. Both of the cytochalasins showed strong cytotoxic activity on tumor cell line SGC-7901 after bio-activity tests.