中文摘要：

近年来研究表明，痤疮不仅是一种皮肤病，也是一些系统疾病或综合征的主要表现，在某些情况下可能反映存在系统异常，并为研究性激素、先天性／获得性免疫、炎症反应及遗传因素的相互作用提供了一个理想的疾病模型。了解这些综合征的分子机制、临床表现及治疗进展有助于深入理解痤疮的发病机制，开发出治疗痤疮的新方法。

英文摘要：

Recent studies have shown that acne is not only a kind of dermatosis but also a main presentation of many systemic diseases and syndromes. In some cases, aene reflects the presence of systemic abnormalities, and can serve as an ideal model for investigations into the interactions among hormones, innate/ acquired immunity, inflammatory response and genetic factors. To learn the progress in molecular mechanisms, clinical manifestations and treatment of ache-associated syndromes will be beneficial to the understanding of acne pathogenesis and development of new therapies for acne.