目的:观察亚低温结合针刺治疗急性重型颅脑创伤后脑梗死患者的疗效。方法:90例患者随机分为亚低温组、针刺组和综合组,每组30例。3组患者均给予常规基础药物及手术治疗,亚低温组行气管切开、呼吸机辅助呼吸、冰毯降温;针刺组采用醒脑开窍针法,针刺内关、水沟、印堂、三阴交、极泉等穴,并随证加减;综合组行亚低温治疗同时加醒脑开窍针刺治疗。治疗4周后,根据神经功能缺损程度标准(NDS)判定疗效,采用Barthel指数评估病人的日常生活活动能力(ADL)。结果:亚低温组、针刺组和综合组神经功能缺损疗效总有效率分别为66.7%(20/30)、40.0%(12/30)和90.0%(27/30),综合组总有效率均明显高于亚低温组和针刺组(均P〈0.05),亚低温组优于针刺组(P〈0.05);各组患者治疗后ADL评分均明显升高(P〈0.01,P〈0.05),亚低温组和综合组较针刺组升高更明显(均P〈0.01)。结论:亚低温组联合针刺与单纯亚低温治疗均可明显减轻创伤后脑梗死患者神经功能缺损,改善日常生活能力,亚低温联合针刺疗效优于单纯亚低温和单纯针刺治疗。
Objective To observe the efficacy on cerebral infarction after acute serious cranial trauma treated with mild-hypothermia and acupuncture.Methods Ninety cases were randomized into a mild-hypothermia group,an acupuncture group and a comprehensive therapy group,30 cases in each one.The conventional basic medication and operation were applied to the patients in all of 3 groups.In the mild-hypothermia group,the tracheotomy,the assisted respiration by respirator and hypothermia with ice blanket were provided.In the acupuncture group,acupuncture for regaining consciousness was provided at Neiguan(PC 6),Shuigou(GV 26),Yintang(GV 29),Sanyinjiao(SP 6),Jiquan(HT 1),etc.The acupoint prescription was modified according to the symptoms.In the comprehensive therapy group,the mild-hypothermia and acupuncture for regaining consciousness were used in combination.In 4 weeks of treatment,according to the neural function deficient scale(NDS),the efficacy was assessed.Barthel index was used to evaluate the activities of daily life(ADL).Results The total effective rates of neurological deficits were 66.7%(20/30),40.0%(12/30) and 90.0%(27/30) in the mild-hypothermia group,the acupuncture group and the comprehensive therapy group separately.The total effective rate of neurological deficits in the comprehensive therapy group was remarkably higher than that in either the mild-hypothermia group or the acupuncture group(both P〈0.05),that in the mild-hypothermia group was better than that in the acupuncture group(P〈0.05).After treatments,ADL score in each group was increased remarkably(P〈0.01,P〈0.05),those in the mild-hypothermia group and the comprehensive therapy group were increased much more apparently compared with that in the acupuncture group(both P〈0.01).Conclusion The comprehensive therapy of mild-hypothermia and acupuncture alleviates remarkably the neurological deficits in traumatic cerebral infarction and improves the activities of daily life.The efficacy of the mi