中文摘要：

目的 研究中药鱼腥草体外抗豚鼠巨细胞病毒的效果和安全性.方法 以金叶败毒和更昔洛韦为对照药物,用细胞病变法和四甲基偶氮唑盐（MTT） 法,检测鱼腥草抗豚鼠巨细胞病毒的最大无毒浓度、最小有效浓度和治疗指数.结果 鱼腥草、金叶败毒和更昔洛韦的最大无毒浓度分别为30,3 mg·mL^-1和100 μg·mL^-1,最小有效浓度分别为300,30和10 μg·mL^-1,治疗指数分别为100,100和10.结论 中药鱼腥草在体外具有抗豚鼠巨细胞病毒的作用,且毒性较小.

英文摘要：

Objective To study the in vitro anti-cytomegalovirus effect of the traditional Chinese medicine houttuynia. Methods The maximum innocuity concentration（TD0）, minimum effective concentration（MEC） and therapeutic index（TI） of houttuynia in its anti-cytomegalovirus activity were detected with the cytopathic assay and MTT method. Jinyebaidu （JYBD） and ganciclovir were used as the control drugs. Results The TD0 of houttuynia, JYBD and ganciclovir were 30, 3 mg·mL^-1 and 100 μg·mL^-1, respectively,the MEC of the 3 drugs were 300,30 and 10 μg·mL^-1,respectively, and their therapeutic indices （TI） were 100,100 and 10, respectively . Conclusion The traditional Chinese medicine houttuynia was shown to be provided with an in vitro anti-cytomegalovirus effect with relatively low drug toxicity.