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Chemistry and pharmacology of Siraitia grosvenorii: A review
  • ISSN号:2095-6975
  • 期刊名称:《中国天然药物:英文版》
  • 时间:0
  • 分类:R284[医药卫生—中药学;医药卫生—中医学] R285[医药卫生—中药学;医药卫生—中医学]
  • 作者机构:[1]Institute of Chinese Material Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China, [2]Hunan University of Traditional Chinese Medicine, Changsha 410208, China
  • 相关基金:This project was supported by the Beijing Joint Project Specific Funds, National Natural Science Foundation of China (Nos. 30873393, 81274112, 81373986) and the Beijing Mu- nicipal Natural Science Foundation (Nos. 7112098, 7132152).
中文摘要:

Siraitia grosvenorii 是对中国的 Guangxi 省地方性的长期的植物。它的水果,通常作为罗 hanguo 知道,并且在中国为咽炎,咽头的疼痛,以及能止咳的疗法的治疗作为自然 sweetener 并且作为传统的药被用于几百年。基于 93 文学来源,这评论在 S 的化学,生物效果,和毒性研究总结了进展。grosvenorii 在过去的 30 年期间。混合物的几个不同的班从 S 的各种各样的部分被孤立或检测。grosvenorii,主要 triterpenoids, flavonoids,多糖,氨基酸,和香精油。从这种导出的摘录或单个混合物的各种各样的类型展出了生物效果的一个宽数组例如能止咳,减轻痰,抗氧化剂, immunomodulatory,保护肝,葡萄糖阴沉,并且抗菌剂。存在研究证明了那从 S 提取,个人加重。grosvenorii 是基本上无毒的。最后,为关于特定的化学药品和 S 的药理学性质的进一步的研究的一些建议。grosvenorii 在这评论被建议。

英文摘要:

Siraitia grosvenorii is a perennial herb endemic to Guangxi province of China. Its fruit, commonly known as Luo hanguo, and has been used for hundreds of years as a natural sweetener and as a traditional medicine for the treatment of pharyngitis, pharyn- geal pain, as well as an anti-tussive remedy in China. Based on ninety-three literary sources, this review summarized the advances in chemistry, biological effects, and toxicity research of S. grosvenorii during the past 30 years. Several different classes of com- pounds have been isolated or detected from various parts of S. grosvenorii, mainly triterpenoids, flavonoids, polysaccharides, amino acids, and essential oils. Various types of extracts or individual compounds derived from this species exhibited a wide array of biological effects e.g. anti-tussive, phlegm-relieving, anti-oxidant, immnnomodulatory, liver-protecting, glucose-lowering, and anti-microbial. The existing research has shown that extracts and individual compounds from S. grosvenorii are basically non-toxic. Finally, some suggestions for further research on specific chemical and pharmacological properties of S. grosvenorii are proposed in this review.

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期刊信息
  • 《中国天然药物:英文版》
  • 北大核心期刊(2008版)
  • 主管单位:中华人民共和国教育部
  • 主办单位:中国药科大学 中国药学会
  • 主编:吴晓明
  • 地址:南京童家巷24号中国药科大学2号信箱
  • 邮编:210009
  • 邮箱:cpucjnm@163.com
  • 电话:025-83271565 83271568
  • 国际标准刊号:ISSN:2095-6975
  • 国内统一刊号:ISSN:32-1845/R
  • 邮发代号:28-306
  • 获奖情况:
  • 国内外数据库收录:
  • 美国国际药学文摘,美国化学文摘(网络版),波兰哥白尼索引,美国生物医学检索系统,美国科学引文索引(扩展库),美国生物科学数据库,中国中国科技核心期刊,中国北大核心期刊(2008版)
  • 被引量:6564