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碳酸氢钠溶液关节腔持续冲洗治疗痛风性膝关节炎的临床研究
  • ISSN号:1000-274X
  • 期刊名称:《西北大学学报:自然科学版》
  • 时间:0
  • 分类:R589.7[医药卫生—内分泌;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]桂林医学院附属医院脊柱骨病外科,广西桂林541001, [2]桂林医学院,广西桂林541004, [3]桂林医学院第二附属医院检验科,广西临桂541100
  • 相关基金:广西壮族自治区教育厅科研资助项目(200911LX302);广西壮族自治区卫生厅自筹基金资助项目(2009037);桂林市科学研究与技术资助开发技术项目(20090204).
中文摘要:

目的:探讨碳酸氢钠溶液在膝关节镜术后关节腔持续冲洗治疗痛风性膝关节炎的疗效。方法:选择桂林医学院附属医院脊柱骨病外科2010年01月至2014年10月因痛风性膝关节炎就诊的患者51(9例双膝,42例单膝其中左膝38例右膝22例,共60膝)例,分为3组进行临床相关实验及治疗;对比不同组数据,评价膝关节镜术后碳酸氢钠溶液关节腔持续冲洗治疗痛风性关节炎的疗效。结果:实验组穿刺的膝关节液p H值较对照组Ⅰ及对照组Ⅱ膝关节液的p H值明显偏高,差异有统计学意义(P〈0.01);ROM评分实验组在治疗干预后明显高于对照组Ⅰ及对照组Ⅱ,差异有统计学意义(P〈0.05)。结论:5%碳酸氢钠溶液在膝关节镜术后持续冲洗膝关节能有效清除关节尿酸结晶,减少残存,降低复发率,相比于传统治疗可有效减轻术后疼痛,改善关节功能。

英文摘要:

Objective:To investigate the curative effect of continuous irrigation of the knee joint cavity with sodium bicarbonate solution on gouty arthritis after arthroscopic surgery. Methods: 51 patients with gouty knee arthritis in Dept. of Spinal Bone Surgery, the Affiliated Hospital of Guilin Medical University from January 2010 to October 2014 were concluded in the study (both knees with gouty arthritis were found in 9 patients, single knees with gouty arthritis in 42 patients). Altogether 60 knees were with gouty arthritis including 38 left knees and 22 right knees. They were divided into 3 groups for treatments. Different sets of data were compared to assess the effects of continuous irrigation of the knee joint cavity with'sodium bicarbonate solution on gouty arthritis after arthroscopic surgery. Results: The pH value of the punctured knee joint fluid in the experimental group was obvious higher than that of the control group, which was of statistical difference (P 〈 0.01); Rom score in the experimental group after treatment intervention was significantly higher than that of the control group, which was of statistical dif- ference (P 〈 0.05). Conclusion: Compared with the conventional treatment, continuous irrigation of the knee joint cavity with 5% sodium bicarbonate solution can effectively remove the uric acid crystals in joints, reduce the residual and the recurrence rate and the postoperative pain, and improve the function of joints as well.

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期刊信息
  • 《西北大学学报:自然科学网络版》
  • 主管单位:
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  • 主编:姚运
  • 地址:西安市太白北路299号
  • 邮编:710069
  • 邮箱:
  • 电话:029-88303833
  • 国际标准刊号:ISSN:1000-274X
  • 国内统一刊号:ISSN:61-1072/N
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  • 被引量:16