次氯酸(HOCl)作为消毒剂被广泛用于日常生活中,人体内内源性HOCl是中性粒细胞来源的髓过氧化物酶与过氧化氢(H_2O_2)共同作用下氯离子发生氧化反应产生的,是一种天然、广谱、速效、低浓度时无毒的抗微生物剂,本文综述了低浓度HOCl的临床研究和使用,讨论了HOCl作为防治组织感染外用杀菌消毒剂的潜在可行性。
As a common disinfection agent, hypochlorous acid is widely used in daily life. Then endogenous hypochlorous acid is produced through the interaction of H2O2 and Chloride ion with the presence of myeloperoxidase from the neutrophils. Hypochlorous acid is a natural anti-microbial agent with broad spectrum, quick acting and low cytotoxicity under low concentrations. This review summarized the clinical study and application of hypochlorous acid.