中文摘要：

重症中暑救治存在一系列问题,如发病机制不清楚、基于外在表现的临床分型过于简单化且与其病理生理过程和预后无内在联系、分层诊断和预后预测指标缺失、针对性治疗规范指导缺乏等,以致重症中暑死亡率和致残率居高不下。本研究团队于2002年开始进行中暑的流行病学调查,在探讨重症中暑脏器损伤规律的基础上,将重症医学理论体系和救治技术运用于重症中暑救治,以转化医学理念展开了重症中暑脏器损伤机制研究,取得了阶段性的研究成果,获得了一系列重症中暑救治关键性技术,这些技术在全国30家医院进行了推广,提高了重症中暑救治能力。

英文摘要：

There exist a series of problems in heat stroke treatment, such as, pathogenesis is still unclear, clinical classification is too simple and has no intrinsic relation with pathophysiological process and prognosis, missing of indexes for hierarchical diagnosis and prognosis prediction, and lack of targeted therapeutic norms. All of these factors could lead to high mortality and disability by heat stroke. Our research team started an epidemiological investigation of heat stroke since 2002. On the basis of discovering organ injury rule, system info and treatment technology on critical medicine were applied to heat stroke treatment. Research on organ injury mechanism for heatstroke was carried out based on translational medicine idea, and periodic research results were also achieved. A series of key technologies for heat stroke treatment were obtained. These technologies were popularized in 30 hospitals across the country, thus improving ability of heat stroke treatment.