现代神经成像技术已经能在活体上获得近似于真实的小脑与大脑结构功能连接特征.近年来的研究已发现小脑在认知、注意、情感和语言等非运动功能方面起到了重要作用.在神经精神疾病中,小脑异常也参与了神经认知损害.本文针对包括老化、癫痫和精神分裂症在内的典型小脑非运动功能异常,从结构、功能和脑连接角度综述了小脑的影像研究进展.对于探索小脑的非运动功能及其在老化和神经精神疾病中的病理生理机制具有重要的科学意义.
The structural and functional connectivity between cerebellum and cerebral cortex could be acquired realistically with neuroimaging techniques. Recent studies showed that the cerebellum played an important role in the non - motor function, including the cognition, attention, emotion and language. In neuropsychological diseases, the cognitive defects associated with abnormality in cerebellum. This review focused on the abnormal non - motor function in aging, schizophrenia and epilepsy, and demonstrated the structural, functional and connected neuroimaging findings in these diseases. The review would be helpful to investigate cerebellar non - motor function and its pathophysiological mechanism in neuropsychological diseases.