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雌激素通过调节EphB4/EphrinB2信号参与破骨细胞分化
  • ISSN号:1006-7108
  • 期刊名称:《中国骨质疏松杂志》
  • 时间:0
  • 分类:R68[医药卫生—骨科学;医药卫生—临床医学;医药卫生—外科学]
  • 作者机构:第二军医大学济南军区临床医学院,山东济南250031
  • 相关基金:国家自然科学基金青年基金项目(30901504)
中文摘要:

目的:观察腓肠肌岛状穿支肌皮瓣治疗胫骨近端骨髓炎伴骨外露的临床效果。方法:回顾性分析2013年1月至2015年6月在我科收治的15例胫骨近端骨髓炎伴骨外露患者,采用彻底清创、用腓肌岛状穿支肌皮瓣进行修复治疗,皮肤缺损面积为5cmx4cm~8cmx6cm.切取皮辫面积为6cmx5cm-9cmx7cm。术后对皮瓣成活率、并发症、膝踝关节功能、皮瓣外观满意度进行随访观察。结果:本组15例中14例肌皮瓣一期愈合,1例二期愈合,术后随访6~18个月无感染复发病例,膝踝关节功能良好。根据改良ASAMI评分系统评价疗效:优10例,良4例,中1例,差0例。结论:腓肠肌岛状穿支肌皮瓣修复胫骨近端骨髓炎伴骨外露具有良好疗效。

英文摘要:

Objective: To observe the clinical curative effects of the medial sural artery perforator island musculocutaneous flap on proximal tibial osteomyelitis combined with bone exposure. Methods: Between Janury 2013 and June 2015, the medial sural artery perforator island musculocutaneous flap were used to reconstruct proximal tibial osteomyelitis combined with bone exposure in 15 patients at our institute. The areas of defect ranged from 5 cmx 4 cm to 8 cmx 7 cm, Flap sizes ranged from 6 cmx 5 cm to 9 cmx 8 cm. The flap survival rate, complication, the function of knee and ankle joint, appearance of satisfaction were followed up. Results: Flaps survived in all patients cases, the muscle flaps in 14 cases healed in phase I and those in 1 cases healed in phase II. There was no recurrence in the follow-up of 6 months to 18 months. There were no stiffness of the joint. According to the modified ASAMI criteria for bone healing, 10 cases were excellent, 4 good, one moderate, zero poor. Conclusion: The medial sural artery perforator island musculocutaneous flao is an effective treatment for oroximal tibial osteomvelitis combined with bone ext~osure.

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期刊信息
  • 《中国骨质疏松杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国民政部
  • 主办单位:中国老年学和老年医学学会
  • 主编:张萌萌
  • 地址:北京市朝阳区望京西园三区309-703
  • 邮编:100102
  • 邮箱:info@china-osteofound.org
  • 电话:010-64727035 64705247
  • 国际标准刊号:ISSN:1006-7108
  • 国内统一刊号:ISSN:11-3701/R
  • 邮发代号:82-198
  • 获奖情况:
  • 国内外数据库收录:
  • 美国化学文摘(网络版),中国中国科技核心期刊,中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:15856