中文摘要：

50岁以上的男性有4种非肿瘤性疾病最常见,包括阴茎勃起功能障碍（erectile dysfunction,ED）、良性前列腺增生（benign prostate hyperplasia,BPH）、心血管疾病和抑郁症,且发病率随着年龄的增长而增高。BPH是导致下尿路症状（lower uri-nary tract symptoms,LUTS）的主要病因,

英文摘要：

Lower urinary tract symptoms secondary to benign prostatic hyperplasia（BPH/LUTS） anderectile dysfunction（ED） are common conditions seen in aging males.Although the exact mechanism ofED combined BPH/LUTS is unknown,treatment with α-adrenergic receptor resistance agents（α-ARAs） that the associations between BPH/LUTS and ED lay the foundation for future therapies and possible pre-ventative strategies.This article has mainly summarized the advancement of epidemiology,basic research and treatment of ED combined with BPH/LUTS with α-receptor blockers and phosphodiesterase-5 inhibitors.