中文摘要：

防御素（defensins）是一类低分子质量抗菌肽,广泛地分布于动物和植物界。小肠潘氏细胞防御素是存在于哺乳动物小肠肠腺底部的潘氏细胞颗粒内的一类抗菌肽,是肠道天然屏障的重要组成部分。作者综述了小肠潘氏细胞防御素的分类、分布、分子特征和抗微生物活性及其在肠道免疫中的作用。

英文摘要：

Defensins are a group of small molecular antimicrobial peptides and distribute mostly in animals and plants. The paneth cells defensins are kinds of antimicrobial peptides which have existed in the paneth cells of some mammal＇s small intes- tinal crypts and have important roles in natural immunity of intestinal tract. The classification, distribution, molecular charac- teristicsm, antimicrobial activities and immune function of paneth cells defensins at home and abroad were summaried.