观察产后甲状腺炎(PPT)患者产后1年内血清转化生长因子β1(TGF—β1)的动态变化发现,PPT患者产后3、6和9个月时血清TGF—β1的水平较同月份对照产妇显著增加,提示TGF—β1参与了针对PPT自身免疫的整个拮抗过程。
A dynamic change of serum transforming growth factor-β1 (TGF-β1) level was observed in patients with postpartum thyroiditis (PPT) during the first postpartum year. TGF-β1 levels were higher in PPT patients at 3, 6 and 9 months of postpartum than those in control postpartum women, suggesting that TGF-β1 appears to be involved in the resistance to the PPT-related autoimmunity.