软骨细胞周基质(pericellular matrix,PCM)是软骨细胞周围的狭窄基质条带,与其包绕的软骨细胞共同组成软骨单位。大量研究表明PCM富含蛋白多糖、胶原蛋白和纤维蛋白,且在调节软骨细胞代谢微环境方面发挥着重要作用。用微管吮吸技术直接检测软骨单位发现,PCM与软骨细胞和软骨细胞外基质的力学特性明显不同。然而,关于PCM的功能还不是十分明确,仍需进一步研究。
Pericellular matrix(PCM) is a narrow tissue region surrounding chondrocytes,which "chondron" with its enclosed cells. A number of studies suggested that PCM is rich in proteoglycans,collagen and fibronectin,and plays an important role in regulating microenvironment of chondrocytes. Direct measures of PCM properties through micropipette aspiration technique showed that PCM was different from mechanical property of chondrocytes and nature extracellular matrix. However,the function of PCM is not clear,and need further study.