中文摘要：

抗菌肽（antimicrobial peptides,AMPs）是生物先天免疫系统的重要组成部分,由核糖体或非核糖体肽合成酶合成,可协助宿主有效应对细菌、真菌、原生生物和病毒等病原生物的胁迫。AMPs具有相对分子质量小、两亲性结构和携带正电荷等理化性质。综述抗菌肽构象、电荷及阳离子度、疏水性与疏水力矩、两亲性及其他属性等方面的研究进展。

英文摘要：

Antimicrobial peptides（AMPs） comprise an important part of the innate immunity system of host organism and provide effective protection for the host against bacteria,fungi,protozoa and viruses.They are synthesized either by ribosomal or non-ribosomal peptide synthetase.Usually,AMPs are positively charged small molecular weight proteins and have both a hydrophobic and hydrophilic side that enables the molecule to enter the membrane lipid bilayer.In this review,recent discoveries on such physicochemical characteristics of AMPs as conformation,cationicity,hydrophobicity,amphipathicity etc.are discussed.