中文摘要：

目的 通过测量各种类型脑卒中患者的踝肱指数（ankle-brachial index ABI），定量评估各类型脑卒中与颅内动脉粥样硬化程度的相关性，探讨ABI是否可作为评估颅内动脉硬化狭窄的指标之一。方法 选取各类型脑卒中住院患者共227例，正常对照组88例。使用博士血管多谱勒超声测量仪，测量所有病例组与对照组的ABI，比较两组受试者的ABI。并分析ABI与脑卒中的相关性。结果 227例脑卒中患者中，动脉血栓形成性脑梗死119例，其ABI为（0.905±0.133）；腔隙性梗死42例，其ABI为（0.908±0.160）；分别与对照组ABI（0.980±0.108）比较，有统计学差异（P〈0.05）。心源性脑栓塞组、蛛网膜下腔出血组、脑出血组的ABI值分别与对照组比较，无统计学差异（P〉0.05）。相关分析显示高血压（OR=3.963）和ABI（OR=2.225）与脑卒中明显相关（P〈0.05）。结论 ABI可反映动脉血栓形成性脑梗死和腔隙性梗死均与脑动脉硬化明显相关，可作为颅内动脉粥样硬化狭窄的初步筛查手段。

英文摘要：

Objective We investigated whether ankle-brachial index （ABI） of stroke patients can be used as a screening method for arterial stenosis in stroke patients. Methods ABI was measured in 227 stroke patients, and 88 normal controls using a Doppler device. After adjusting other risk factors, the influence of ABI in stroke was evaluated. Resuits There were statistical differences in ABI between arterial thrombosis cerebral infarction （n = 119, ABI = 0.905±0. 133）, lacunar infarction （n=42, ABI =0.908±0. 160） and normal control （n =88, 0.980±0.108）, （P =0.002、0.015 respectively）. There were no statistical differences in ABI between cardiogenic cerebral embolism, subarachnoid hemorrhage, cerebral hemorrhage and normal control. After adjusting other risk factors including sex, age, diabetes, hyperlipemia, coronary artery disease and smoking, hypertension （odd ratio = 3.963 ）, and ABI（ odd ratio = 2.225 ） were significantly associated with the presence of stroke. Conclusions ABI can reflect the strong relationships between arterial thrombosis cerebral infarction, lacunar infarction and cerebral atherosclerosis, and it can be taken as preliminary screening means of cerebral atherosclerosis.