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Association of Bisphenol A Exposure with Circulating Sex Hormone Concentrations in Men and Postmenopausal Women
  • ISSN号：0254-6450
  • 期刊名称：《中华流行病学杂志》
  • 时间：0
  • 分类：Q753[生物学—分子生物学] S852.21[农业科学—基础兽医学;农业科学—兽医学;农业科学—畜牧兽医]
  • 作者机构：[1]Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health, Ruijin Hospital, Shanghai Jiaotong University Medical School, E-Institute of Shanghai Universities, Shanghai 200025, China, [2]Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai institute of Endocrine and Metabolic Diseases, Department of Endocrinology and Metabolism, Ruijin Hospital, Shanghai Jiaotong University Medical School, Shanghai 200025, China
  • 相关基金：This study was supported by the grants from Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health （1994DP131044）, National Natural Science Foundation of China （No.81170739, 81170719, 81270877, 81222008, 81200563）, Shanghai New Excellent Youth Program （XYQ2011009）, Shanghai Health Bureau （2011293） and Shanghai Committee of Science and Technology （12PJ1407700）, EFSD-CDS- Lilly Program for Collaborative Research between China and Europe （2011）.
作者： LI Mian[1], WANG Tian Ge[1], XU Yu[1,2], ZHANG Jie[1], XU Bai Hui[1], XU Min[1,2], CHEN Yu Hong[1,2], LU Jie Li[1,2], Bi Yu Fang[1,2], WANG Wei Qing[1,2], GU Yan Yun[1,2], NING Guang[1,2]
关键词： 激素浓度, 双酚A, 循环性, 绝经后, 妇女, 男性, 促卵泡激素, 协会
中文摘要：

<正>A total of 1 116 middle-aged and elderly men and 1 442 postmenopausal women were recruited in this study.Whether bisphenol A exposure was associated with circulating sex hormone concentrations was studied.Univariate analysis revealed that the urinary bisphenol A concentration was negatively correlated with the serum levels of luteinizing hormone(β=-0.061,P<0.0001)and follicle-stimulating hormone(β=-0.086,P<0.0001)in men,

英文摘要：

A total of 1 116 middle-aged and elderly men and 1 442 postmenopausal women were recruited in this study. Whether bisphenol A exposure was associated with circulating sex hormone concentrations was studied. Univariate analysis revealed that the urinary bisphenol A concentration was negatively correlated with the serum levels of luteinizing hormone （B=-0.061, P〈0.0001） and follicle-stimulating hormone （B=-0.086, P〈0.0001） in men, and with the serum levels of follicle-stimulating hormone （B=-0.037, P=0.018） and sex hormone-binding globulin （B=-0.043, P=0.006） in women. However, no significant association was observed between the serum levels of urinary bisphenol A and circulating sex hormone after adjustment for the potential confounders.

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期刊信息
  • 《中华流行病学杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编：
  • 地址：北京昌平区昌百路155号传染病所B115
  • 邮编：102206
  • 邮箱：lxbonly@public3.bta.net.cn
  • 电话：010-58900730
  • 国际标准刊号：ISSN：0254-6450
  • 国内统一刊号：ISSN：11-2338/R
  • 邮发代号:2-73
  • 获奖情况:
  • 1999年预防医学会优秀期刊一等奖,1996年中华医学会中华预防医学会优秀期刊奖
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,美国生物医学检索系统,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊（2004版）,中国北大核心期刊（2008版）,中国北大核心期刊（2011版）,中国北大核心期刊（2014版）,中国北大核心期刊（2000版）
  • 被引量:62798