中文摘要：

研究了利用二氯磷酰胆碱（PC-2C1）以及十八烷基二甲基氯硅烷（C18）和1，6-己二异氰酸酯（HDI），将仿细胞膜磷酰胆碱（Pc）基团化学接枝到盖玻片表面的三条新途径，（DPC-2C1直接与玻璃表面硅羟基反应，（II）HDI先与玻璃表面硅羟基反应、水解产生的端氨基再与PC-2C1反应进行Pc接枝，（III）C18与玻璃表面硅羟基反应后再进行II的处理步骤。通过测定改性表面的动态接触角（DCA）和x射线光电子能谱（XPS）对改性效果进行评价。结果表明，三条途径均成功地实现了Pc基团在盖玻片表面接枝改性，其中接枝HDI后再与二氯磷酰胆碱反应的途径PC接枝率较高。

英文摘要：

Cell membrane mimetic phosphorylcholine （PC） groups were grafted onto cover glass surfaces via three new routes using phosphorylcholine dichloride （PC -2C1） , chlorodimethyl -n -octadecylsilane （Cls） and 1,6 - diisoeyanatohexane （HDI） as the reagents. Route I, the surface - silanol group of the glass was reacted directly with PC - 2C1. Route II, the surface - silanol group was reacted with HDI, and then the resulted end - amine group after hydrolysis was reacted with PC - 2C1.. Route III, Cis was graf- ted grafted first, and then followed with the procedures of route II. The effects of surface modification were evaluated through the measurements of dynamic contact angle （ DCA ） and X - ray photoelectron spectroscopy （XPS）. The results indicated that, the three routes in this paper could graft PC groups onto the surfaces of cover glasses successfully, while route II or III could obtain higher PC coverage on the sur- face and tunable hydrophilicity.