中文摘要：

采用牙种植术将36颗牙种植体植于6只杂种犬双侧下颌缺牙区,同时在种植体近中造3.5 mm×3.5 mm×3.5mm的骨缺损,然后填入β-TCP/PRF混合物、β-TCP,另设空白对照组（不做任何处理）于各骨缺损区,分别于种植术后4、8、12周各处死2只犬,行大体、X线及组织学观察各个时期各组骨缺损区的成骨情况。植入的36颗种植体无脱落,无明显不良并发症发生。β-TCP/PRF混合物是一种良好的骨修复材料,具有促进新骨形成的作用,有利于骨组织的愈合。

英文摘要：

36 dental implants were separately implanted in each side of the mandibule of 6 dogs.At the same time,a 3.5 mm×3.5 mm×3.5 mm size bone defect was created in the mesial aspect of each implant.3 kinds of substitutes were grafted in the bone defects：β-TCP/PRF compounds,β-TCP and blank control（do not make any deal）.Every 2 dogs were sacrificed at 4,8 and 12 weeks after the implantation,and gross observation,X-rays and histopathology were examined.The results showed 36 dental implants did not fall off,and no severe complications occurred.So β-TCP/PRF is a better bone repair material with the promotion of new bone formation and the elevation of healing quality.