以卵巢浆液性癌中砂粒体矿化为研究对象,采用偏光显微镜、扫描电镜及其能谱、X射线粉晶衍射、傅立叶变换红外光谱和高分辨透射电子显微镜,对原位和分离处理样品的表面形貌、结构和矿物成分进行了观察测试。结果表明,卵巢浆液性癌中砂粒体具同心层状结构,矿化物质由纳米尺寸水草酸钙石和碳羟磷灰石两种物相组成,前者沉积在砂粒体内部,结晶度相对较高,后者沉积在砂粒体外层,结晶度差。
Ovarian cancer is one of the common malignant tumors in female reproductive organs. Psammoma bodies occurring in cell population is considered to be a phenomenon of ovarian serous carcer. In this paper,psammoma bodies from ovarian serous carcinomas were investigated by using SEM,EDAX,XRD,FTIR and HRTEM. The results show that the mineralized matter of the psammoma bodies with the concentric lamellated structure is composed of nano-size whewellite and carbonate hydroxylapatite. The former is deposited in the inner part of the psammoma body in a relatively high crystallinity,whereas the latter in the outer part in a low crystallinity.