中文摘要：

B细胞抗原表位的研究对免疫原性多肽和新型疫苗分子的设计都起着指导作用，同时也有利于诊断试剂的开发以及临床疾病的诊断。本文综述了近年来实验确定和理论预测B细胞蛋白质抗原表位的常用方法，以及B细胞抗原表位分析的研究方法。

英文摘要：

Mapping of B-cell epitope plays a guiding role on the design of immunogenic peptides and new molecular vaccine. At the same time, it is also conducive to the development of diagnostic reagents and clinical disease diagnosis. Both of the present common methods of experimental determination and theorical prediction of B cell antigen epitope and the methods of B cell epitope analysis were summarizied in this paper.