中文摘要：

由 Cunninghamella echinulata 的 pregnane-3,16,20-triol (1 ) 的微生物引起的转变以前负担得起四 unreported polyhydroxylated 类固醇，也就是 pregnane-3,14,16,20-tetrol (2 ) ， pregnane-3-oxo-14， 16,20-triol (3 ) ， pregnane-3-oxo-7,16,20-triol (4 ) ，和 pregnane-3,7,16,20-tetrol (5 ) 。这些代谢物的结构借助于分光镜的分析(1D 和 2D NMR 以及 HRESIMS 分析) 被建立。

英文摘要：

Microbial transformation of pregnane-3β,16β,20-triol （1） by Cunninghamella echinulata afforded four previ- ously unreported polyhydroxylated steroids, namely pregnane-3β,14a,16β,20-tetrol （2）, pregnane-3-oxo-14a, 16β,20-triol （3）, pregnane-3-oxo-7β,16β,20-triol （4）, and pregnane-3fl,7β,16β,20-tetrol （5）. The structures of these metabolites were established by means of spectroscopic analysis （1D and 2D NMR as well as HRESIMS analysis）.