中文摘要：

近年来,与化疗经典用药氟尿嘧啶相关的肿瘤治疗方案层出不穷.文章通过文献检索并参考多个指南,归纳了近十年来氟尿嘧啶类抗肿瘤药物相关的常用化疗方案和常见不良反应特点、不良反应发生机制及临床预防或对症处理的方法.以指导化疗方案的选择,充分保证治疗的安全性及有效性.同时,为今后新化疗方案的研究提供一些参考依据.

英文摘要：

Varieties of chemotherapeutic regimens based on fluorouracil have been recently developed.This review summarized widely used regimens of fluorouracil based chemotherapy in this decade.The common side effects,their mechanisms and clinical prevention and symptomatic treatment for these adverse reactions were also discussed.Therefore,this review will provide guidance for regimen selections,and improve the efficacy and safety of chemotherapy.In addition,the detailed information and data presented in this paper may be helpful in the development of new chemotherapy regimens.