芦丁作为黄酮类主要成分的代表, 受到科研界的高度重视。目前对芦丁的研究比较成熟,也取得了显著的效果。本文概括了芦丁的来源、结构及理化性质以及从各种原料中提取并测定芦丁的方法及其生物活性,重点介绍了芦丁对几种具有代表性的文明病:痛风、肥胖、心血管疾病和糖尿病的作用。并提出加强芦丁对机体功能,尤其是信号传导作用的体内研究。
As a major representative component of flavonoids, rutin has gained high attention in the scientific field. At present, the studies of rutin have achieved remarkable results. In this article, the sources, structures, physicochemical properties, biological activity, and extraction and determination methods of rutin from a variety of raw materials are summarized. Meanwhile, the roles of rutin in several typical civilization diseases such as gout, obesity, cardiovascular diseases and diabetes are also discussed. In order to strengthen the function of rutin on the body, the role of rutin in signal transduction in vivo is also proposed.