近红外光由于具有良好的生物组织穿透性且对组织几乎无损伤等优点,在生物医学领域展现了光明的应用前景。进人生物体内的近红外光要发挥诊疗作用.其前提是需要可吸收,转换近红外光的纳米材料或器件。本文综述了近红外光驱动的纳米材料和器件的研究进展,主要包括稀土上转换发光纳米材料、980nm激光驱动的发电机以及光热转换纳米材料,重点介绍了它们的生物应用进展;最后指出了目前存在的问题和发展方向。
Near-infrared (NIR) light has great potential in biomedical application due to its advantages such as deep penetration depth and low photodamage to biological tissues. If we want to use NIR light that has entered animal body, for in-vivo diagnosis and therapeutic intervention, a prereqmslte IS to obtain nanomaterials and/or nanodevices that can absorb or convert NIR light. This paper reviews the recent research progress in NIR-light- driven nanomaterials and/or nanodevices, including up-converting rare-earth nanophosphors, 980-nm laser-driven generator, and photothermal nanoagents. The main attention has been given to the biological application of these nanomaterials and/or nanodevices. At last, the present problems and the future development trends are pointed out.