对比研究了经不同时间高温石墨化处理后的C/C复合材料有毒物质含量及材料对成骨细胞生长的影响。结果表明,延长高温处理时间可以去除有毒物质As,Pb和减少有毒Hg,Cd,Al等含量。经过较短时间(4,8h)处理后的C/C复合材料表面成骨细胞生长缓慢,有明显的毒性作用,而超过较长时间(12,16h)处理后的C/C复合材料表面成骨细胞生长良好。延长C/C复合材料高温处理时间可以提高其生物相容性。
The effect of the toxic substances of carbon/carbon composites by different graphitization treatment times and their impact on osteoblast growth was studied.The results show that prolonging heat treatment can remove toxic substances As and Pb,and reduce Hg,Cd,Al,and other toxic contents.In addition,osteoblasts slowly grow by short time(4,8h)high-temperature treatment and show an obvious toxic effect,but osteoblasts grow well on the carbon/carbon composite surface by long time(12,16h)high-temperature treatment.Thus,extended heat treatment can significantly improve the biocompatibility of the carbon/carbon composites.