目的探讨高血压病和绝经后妇女骨密度的相关性。方法选择福州地区绝经后妇女464例,用双能X线骨密度仪检测正位第2~4腰椎、左侧股骨颈、大转子和Ward’s三角区骨密度;问卷调查受试者的年龄、绝经年龄、身高、体重、血压等情况。结果①高血压组绝经后妇女年龄、体重明显高于非高血压组(P〈0.01)。②高血压组骨质疏松症患病率65.71%、非高血压组骨质疏松症患病率59.88%,两者比较无明显差异(P〉0.05)。③高血压组股骨颈(0.789±0.112)、ward’s三角区(0.629±0.139)骨密度明显低于非高血压组股骨颈(0.818±0.121)、Ward’s三角区(0.655±0.138)骨密度(P〈0.05),高血压组第2~4腰椎、大转子骨密度与非高血压组比较无明显差异(P〉0.05)。结论高血压病与绝经后妇女的骨密度存在相关性,高血压病是导致绝经后妇女低骨密度的一个危险因素。
Objective To investigate the correlation between hypertension and bone mineral density (BMD) in postmenopausal women. Methods In 464 cases of postmenopausal women in Fuzhou region, the BMD of the 2-4 lumbar spine, left femoral neck, greater trochanter and Ward's area were measured with dual-energy X-ray absortiometry. And age, menopausal age, height, weight, blood pressure and so on were surveyed. Results (!) Hypertensive group of postmenopausal women were signifieantly higher in age, weight than non-hypertensive group (P 〈 0.01 ). (2) Hypertensive group of osteoporosis incidence was 65.71%, and non-hypertension group of osteoporosis incidence was 59.88% .There is no significant difference between the two groups (P 〉 0.05). (3) Hypertension group was significantly lower in the BMD of femoral neck than non-hypertension group (P 〈 0.05); hypertension group was significantly lower in the BMD of Ward's area than non-hypertension group (P 〈 0.05) . No significant difference was found in the BMD of lumbar spine, trochanter compared hypertension group to nonhypertension group. Conclusion Hypertension is associated with BMD in postmenopausal women. Hypertension is a risk factor for low bone mineral density in postmenopausal women.