中文摘要：

目的 探讨可视化角膜生物力学分析仪（corneal visualization scheimpflug technology,Corvis ST）测量眼内压（intraocular pressure,IOP）的重复性,及与非接触眼压计（non-contact tonometr,NCT）和动态轮廓眼压计（dynamic contour tonometry,DCT）测量结果的一致性。方法 选取正常角膜志愿者91例（91眼）。分别应用Corvis ST,NCT和DCT进行眼内压测量,每种仪器测量3次。采用单因素方差分析比较3种不同眼压计测量的IOP结果,组内相关系数（intraclass correlation coefficient,ICC）评估3种仪器各自测量眼内压的可重复性;Bland-Altman分析比较3种仪器测量IOP的一致性;Pearson双变量相关分析眼压测量结果间的相关性。结果 IOPCor、IOPNCT和IOPDCT的均值分别为（13.39±2.48）mm Hg（1 mm Hg=0.133 k Pa）,（13.94±2.32）mm Hg和（17.26±2.00）mm Hg,差异有统计学意义（F=76.949,P〈0.001）。相关性分析显示,3种测量仪器所测眼压结果存在明显相关性（P均〈0.001）。IOPCor、IOPNCT和IOPDCT科隆巴赫系数（Cronbach＇sα）分别为0.94、0.91和0.94;组内相关系数ICC分别为0.83、0.76和0.83。Bland-Altman一致性分析显示,组内偏差,IOPCor与IOPNCT为（-0.5±1.8）mm Hg;IOPCor与IOPDCT为（-3.9±2.1）mm Hg;IOPDCT与IOPNCT为（-3.3±2.2）mm Hg,其一致性界限区间分别为（-4.1~3.0）mm Hg、（-7.9~0.2）mm Hg和（-7.6~1.0）mm Hg。结论 Corvis ST能够有效测量眼内压且测量重复性好,与NCT测量结果具有较好的一致性,但与DCT测量结果存在差异。

英文摘要：

Objective To explore the repeatability of the Corneal Visualization Scheimpflug Technology （Corvis ST） for measuring intraocular pressure （IOP）, and compare the results of Corvis ST with the results of noncontact tonometer （NCT） and dynamic contour tonometer （DCT）. Methods Ninety-one eyes from 91 healthy subjects were included in this study. All the right eyes were chosen for IOP measurement using Corvis ST, NCT and DCT, respectively, and each measurement repeated three times. The IOP results of three different tonometers were analyzed with ANOVA, and the intraclass correlation coefficient （ICC） was used to evaluate the repeatability of these three methods; Bland-Altman was used to evaluate the consistency of IOP results, and the correlation relationship between the IOP results were analyzed by Pearson correlation analysis. Results The mean values of IOPcor, IOPNCT and IOPDCT were （13.39 ± 2.48） mmHg （1 mmHg=0.133 kPa）, （13.94 ± 2.32） mmHg and （17.26± 2.00） mmHg, respectively. The difference were statistically significant （F=76.949, P 〈 0.001, ANOVA）. Correlation analysis showed that three tonometers measured IOP results had significant correlation between each other （P 〈 0.001）. The Cologne Bach coefficient （Cronbach＇s α ） of IOPcor, IOPNCT and IOPDcr were 0.94, 0.91 and 0.94, respectively; and ICC were 0.83, 0.76 and 0.83, respectively. Bland-Altman consistency analysis showed that in group IOPCor and IOPNCT, the deviation was （-0.5± 1.8） mmHg, IOPcor and IOPCOr was （-3.9±2.1） mmHg, IOPocT and IOPNCT was （-3.3 ± 2.2） mmHg, the consistency limit intervals were （-4.1±3.0） mmHg, （-7.9-0.2） mmHg and （-7.6- 1.0） mmHg, respectively. Conclusion Corvis ST can effectively measure the IOP with good measurement repeatability. The relationship with NCT measurement results shows good consistency, but there still exist differences with DCT measurement results.