中文摘要：

从《内经》对腧穴的原始定义与定位方法及热敏灸临床证据入手，论述腧穴“敏化状态说”。腧穴具有状态之别，即“静息”与“敏化”两种功能状态，敏化态腧穴是疾病在体表的反应部位，也是治疗疾病的最佳针灸部位，即腧穴是与疾病过程相关的体表特定的敏感部位，具有治疗疾病的较佳功能。因敏化态腧穴具有动态变异性，临床上只能应用《内经》中粗定位与细定位（探感定位）的二步定位法才能准确定位，而不能仅仅依靠骨度分寸定位或体表标志定位的一步到位法。腧穴的本质属性具有功能状态之别，而不仅仅是固定部位之别。

英文摘要：

To discuss the hypothesis of the sensitization state of acupoints based on the original definition and the localization method of acupoint from Internal Classic as well as the clinical evidence of beat-sensitive moxibustion. Aeupoints are different in the states, named resting and sensitization. The aeupoints of sensitization state are the reactive sites of disease on the body surface, also the best sites for acupuncture and moxibustion treatment. The acu- points are the specific sensitive sites on the body surface relevant with diseases with the best therapeutic effects. Hence, the acupoints of sensitization state are of dynamic variability. In clinical application, only the two-step Iota tion method, preliminary and accurate localizations （sensitive probing localization） from Internal Classic can localize the acupoints precisely, rather than one-step location method such as proportional measurement or body surface landmark localization. The nature and property of acupoints are different based on the functional state, not just on the fixed locations.